Read the sentences below. I– The Food and Drug Administration had approve...

Read the sentences below.

I– The Food and Drug Administration had approved marketing of the weight–loss drug lorcaserin, the first prescription anti–obesity medication to win the FDA?s blessing since the agency approved orlistat in 1999.
II– The U.S. Justice Department?s civil fraud division is investigating claims that CVS Caremark wrongly refilled prescriptions and billed insurers without the knowledge or the approval of its customers.
III– Warning signs of a heart attack often includes discomfort at the center of the chest that last more than a few minutes or comes and goes; also possible are pain or discomfort in the arms, back, neck, jaw or stomach; a cold sweat; and shortness of breath.

According to the context, choose the alternative in which the underlined verb is used correctly.